內容簡介

Basic Virology, 4th Edition cements this series’ position as the leading introductory virology textbook in the world. It’s easily read style, outstanding figures, and comprehensive coverage of fundamental topics in virology all account for its immense popularity.

This undergraduate-accessible book covers all the foundational topics in virology, including:

The basics of virology
Virological techniques
Molecular biology
Pathogenesis of human viral disease
The 4th edition includes new information on the SARS, MERS and COVID-19 coronaviruses, hepatitis C virus, influenza virus, as well as HIV and Ebola. New virological techniques including bioinformatics and advances in viral therapies for human disease are also explored in-depth. The book also includes entirely new sections on metapneumoviruses, dengue virus, and the chikungunya virus.

目次
Preface
Acknowledgements      

PART I             VIROLOGY AND VIRAL DISEASE   
Chapter 1          Introduction – The Impact of Viruses on Our View of Life         
Chapter 2          An Outline of Virus Replication and Viral Pathogenesis
Chapter 3          Virus Disease in Populations and Individual Animals
Chapter 4          Patterns of Some Viral Diseases of Humans     

PART II           BASIC PROPERTIES OF VIRUSES AND VIRUS–CELL INTERACTION           
Chapter 5          Virus Structure and Classification         
Chapter 6          The Beginning and End of the Virus Replication Cycle  
Chapter 7          The Innate Immune Response: Early Defense Against Pathogens
Chapter 8          Strategies to Protect Against and Combat Viral Infection

PART III          WORKING WITH VIRUS
Chapter 9          Visualization and Enumeration of Virus Particles           
Chapter 10        Replicating and Measuring Biological Activity of Viruses         
Chapter 11        Physical and Chemical Manipulation of the Structural Components of Viruses
Chapter 12        Characterization of Viral Products Expressed in the Infected Cell
Chapter 13        Viruses Use Cellular Processes to Express their Genetic Information

PART IV          REPLICATION PATTERNS OF SPECIFIC VIRUSES
Chapter 14        Replication of PositiveSense RNA Viruses
Chapter 15        Replication Strategies of RNA Viruses Requiring RNAdirected mRNA Transcription as the First Step in Viral Gene Expression
Chapter 16        Replication Strategies of Small and Mediumsized DNA Viruses
Chapter 17        Replication of Some Nuclearreplicating Eukaryotic DNA Viruses with Large Genomes
Chapter 18        Replication of Cytoplasmic DNA Viruses and “Large” Bacteriophages
Chapter 19        Retroviruses: Converting RNA to DNA
Chapter 20        Human Immunodeficiency Virus Type 1 (HIV1) and Related Lentiviruses
Chapter 21        Hepadnaviruses: Variations on the Retrovirus Theme

PART V           MOLECULAR GENETICS OF VIRUSES
Chapter 22        The Molecular Genetics of Viruses
Chapter 23        Molecular Pathogenesis
Chapter 24        Viral Bioinformatics
Chapter 25        Viruses and the Future – Problems and Promises

Appendix – Resource Center    
Technical Glossary
Index